CD8A and infection: In another work, we observed that the remaining MDSCs in immunized and infected mice still have the capacity to strongly shape the immune response, since depletion of MDSCs with 5 fluorouracil (5FU) at day 15 post-infection in immunized mice caused a notable increase of the CD8 response and also affected dendritic cells and CD4+Foxp3+ regulatory T cells (Gamba et al., 2021).