The alteration of TNF-α-induced, lung fibroblast (LF) pro-inflammatory phenotype in high-fat and high-fructose (HFHF)-induced pulmonary fibrosis was found to be possibly mediated by DOCK2-regulated PI3K/AKT and NF-κB pathways (Qian et al., 2022b). Here, DOCK2 is linked to pulmonary fibrosis.