GSTM1 and asthma: In contrast, two large cohort studies, the Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) (Imboden et al., 2008) (n = 4,422), and the Avon Longitudinal Study of Parents and Children (ALSPAC) (Minelli et al., 2010) in the United Kingdom (n = 7,262), did not find evidence of associations between GSTM1 or GSTT1 genotypes and asthma.