Buzhong Yiqi decoction, Kuibi decoction, and Danggui Buxue decoction significantly inhibit tumor necrosis factor-a, IL-6, IL-10, and transforming growth factor-b1 in CFS patients (Shin et al., 2004; Chen et al., 2010; Miao et al., 2022). The gene discussed is IL10; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.