Similarly, decursinol angelate (DA), an AGN-derived compound, inhibited pro-inflammatory cytokines associated with cancer cell proliferation, including TNF-α (Kim et al., 2010) while decursin blocked lipopolysaccaride-induced expression of MCP-1, IL-8, TNF-α, and IL-1β in cells and attenuated IL-1β and TNF-α (Kim et al., 2006). This evidence concerns the gene CXCL8 and cancer.