Recently, using a model of severe ischemia/reperfusion-induced acute kidney injury (AKI) that progresses to chronic kidney disease (CKD) and tubulointerstitial fibrosis, we showed by Western blot analysis that DDR1 is upregulated and activated both in the acute and chronic phases of kidney injury (Borza et al., 2022a). This evidence concerns the gene DDR1 and chronic kidney disease.