In the context of kidney injury and disease, immunohistochemical analysis of DDR1 levels and localization showed that this receptor is upregulated in: 1) proximal tubule cells of subjects with transplant acute kidney injury (Chiusa et al., 2019); 2) cellular crescents as well as parietal epithelial cells and podocytes in glomerulonephritis (Kerroch et al., 2012; Moll et al., 2018); 3) parietal epithelial cells and distal tubule cells in Alport syndrome (Richter et al., 2019); and 4) tubule cells in diabetic nephropathy (Moll et al., 2019). Here, DDR1 is linked to Alport syndrome.