They participate in the regulation of immune infiltration by regulating the expression of BMPR1A, GLB1, GRM4, and KCNN3. In GSE48552, 10 miRNAs were detected from six early-stage AD patients and six late-stage AD patients, and four miRNAs had different expression levels in different disease states (Figure 10B). This evidence concerns the gene KCNN3 and Alzheimer disease.