GSDMC and lung adenocarcinoma: Meanwhile, the impact of the GSDM on the occurrence and prognosis of lung adenocarcinoma (LUAD) was evaluated by Wei J et al. The results indicated that GSDMC is significantly upregulated in LUAD tissues and the overexpression of GSDMC was an independently negative prognostic factor in patients with LUAD (Wei et al., 2020).