ADP potentially exhibits its effect by regulating the extracellular signal-regulated protein kinase (ERK1/2) and glutamic-oxaloacetic transaminase 1 (GOT1), thereby causing S-phase arrest, DNA damage, colony formation and migration inhibition, ROS induction, and caspase-mediated apoptosis to ultimately suppress tumor growth (Wang et al., 2019; Mehraj et al., 2022a). The gene discussed is GOT1; the disease is neoplasm.