The expression of TRIM11 was found to be significantly increased in ovarian cancer tissues, and knocking down TRIM11 affected the expressions of apoptosis-related proteins (Bcl-2 and Bax) and invasion-related proteins (MMP-2 and MMP-9) and reduced the phosphorylation levels of ERK and AKT (Chen et al., 2017). The gene discussed is TRIM11; the disease is ovarian cancer.