AKT1 and urinary bladder cancer: Xiaojuan Xie et al. showed that TRIM26 knockdown significantly reduced the levels of p-Akt, phosphorylated glycogen synthase kinase 3β (GSK-3β) (p-GSK3β), β-catenin, and c-Myc in bladder cancer cells, and inhibited the proliferation, invasion and migration of bladder cancer cells through the Akt/GSK3β/β-catenin pathway (Xie et al., 2021).