NFKB1 and cancer: Naringin can be a useful dietary supplement for reducing the risk of nephrotoxicity caused by anticancer drugs like cisplatin in cancer chemotherapy. Cisplatin-induced renal dysfunction can be mitigated with naringin supplementation. During cisplatin toxicity, naringin was able to restore redox equilibrium, suppressing inflammation, NF-kB activation, and apoptosis.