The results showed that NFE2L2 was lowly expressed in STAD tumor tissue (p < 0.001), while SLC31A1 and GCSH genes were highly expressed in STAD tumor tissue (p < 0.01), and there was no significant difference in the expression of NLRP3 between the two groups (p > 0.05). This evidence concerns the gene NLRP3 and gastric adenocarcinoma.