TREM1 expression is associated with tumor-infiltrated myeloid-derived immune cells, particularly with PMN, Mφ, and at a lower degree, with microglia.2,8,34–36 Our analysis revealed that TREM1 expression is a valuable biomarker of glioblastoma progression and, according to the mini-ontology analysis, positively correlates with immunosuppressive, pro-inflammatory, and angiogenic tumor phenotype in a grade-dependent manner. The gene discussed is TREM1; the disease is glioblastoma.