AKT1 and psoriasis: The Khib proteins identified in peripheral blood from patients with immunoglobulin A (IgA) nephropathy aggregate in the interleukin-17 (IL-17) signaling pathway and phagosome class (29), and they were also observed to be enriched in the PI3K-Akt signaling pathway in psoriasis skin lesions, which is associated to psoriasis progression (24).