Another study describes a “Systemic Inflammatory Index” (SII), which is obtained by multiplying blood platelet count and neutrophil count and dividing by lymphocyte blood counts (P x N/L) (41), and the last study describes an “Immunoscore” based on the expression of CD3+ and CD8+ cells in the tumor specimen, using IHC (58). The gene discussed is CD8A; the disease is neoplasm.