CAMK4 and acquired epidermolysis bullosa: When investigating for an overlap among the three models, we found that the kinase activation signatures are distinct across the three mouse models of pemphigoid diseases (Figure 1D): More specifically, only 2 kinases showed an overlap: Calcium/calmodulin-dependent protein kinase type IV (Camk4) between antibody transfer-induced MMP and immunization-induced EBA, and serine/threonine-protein kinase ATR (Atr) shared between antibody transfer-induced and immunization-induced EBA.