An additional consideration is the relative availability of the Cpd1, Cpd2, and Cpd3 antigens during in vivo infection, as the pulmonary compartment is the initial site of infection, Most relevant to these studies is the RNAseq data of infected mouse lungs shows the median transcript rank of Cpd1 to be over ten times higher than Cpd2 or Cpd3. Here, PMPCA is linked to infection.