It was also revealed that some GSDMB-regulated genes, cytokines, and chemokines, such as TGF-β1, MMP-9, cysteinyl leukotrienes (LTC4/D4/E4), CXCLs, and so on, contribute to inflammation and airway remodeling in asthma (109, 112, 114, 115). This evidence concerns the gene GSDMB and asthma.