ABCB1 and acute coronary syndrome: ABCB1 polymorphisms and abnormal activity of P-glycoprotein affect clopidogrel’s absorption and transport, and TRITON-TIMI 38 trail (40) had detected that the ABCB1 3435 TT genotype attenuates platelet inhibition and increases the risk of recurrent ischemic events in acute coronary syndrome patients receiving clopidogrel treatment.