PRAME and leukemia: Of the 19 patients with active disease, including those leukemias without elevated TAA/ABL1, the blood levels of WT1/ABL1, PRAME/ABL1, and BIRC5/ABL1 exceeded healthy donors (p<0.0001, p=0.0286, and p=0.0064 respectively, Figures 2B-D).