Based on known cell type markers, we identified and classified 5 cell types displayed by t-distributed stochastic neighbor embedding (t-SNE) as follows: tumor cells (EPCAM, PAX8, WT1), myeloid cells (CD14, AIF1, CSF1R), NK/T cells (CD2, CD3E, CD3D, GZMA, GNLY, NKG7), B lymphocytes (CD19, CD79A, MS4A1), and cancer-associated fibroblasts (CAFs) (PDPN, DCN, THY1) (Figures 1C, D). The gene discussed is CD3D; the disease is cancer.