To evaluate whether BCG and Mtb-m18b–infected EpCAM+/ABCG2+ CSCs may also undergo cell death by apoptosis and pyroptosis due to intracellular replication of the pathogen, the infected cancer cells (104/ml) were grown in vitro for 16 days to find out the day when pathogen replication goes down with associated increase in host cell death. This evidence concerns the gene ABCG2 and cancer.