The results demonstrated that the TCR Richness Score was notably higher in both the PTPRD/PTPRT single-mutant and double-mutant cancers, than in WT patients (P < 0.001), while there was no statistical difference between PTPRD/PTPRT single-mutant and double-mutant patients (P > 0.05) (Figure 7E). Here, PTPRD is linked to cancer.