Prognostic network maps of CRGs indicate LIAS, FDX1, SLC31A1, and ATP7B as protective factors in HCC, while NFE2L2, NLRP3, ATP7A, LIPT1, DLD, DLAT, PDHA1, PDHB, MTF1, GLS, CDKN2A, DBT, GCSH, and DLST are the risk factors (Figure 3P). The gene discussed is PDHB; the disease is hepatocellular carcinoma.