Prognostic network maps of CRGs indicate LIAS, FDX1, SLC31A1, and ATP7B as protective factors in HCC, while NFE2L2, NLRP3, ATP7A, LIPT1, DLD, DLAT, PDHA1, PDHB, MTF1, GLS, CDKN2A, DBT, GCSH, and DLST are the risk factors (Figure 3P). This evidence concerns the gene CDKN2A and hepatocellular carcinoma.