As shown in Table 1, before 12 weeks of Tai Chi intervention, we observed that there are significant differences in FBG, 2 hPG, HbA1C, HbA1, FINs, and HOMA-IR among PDM-C, PDM-TC, and NG groups (P<0.05 or P<0.01), suggesting that the blood glucose and insulin resistance in PDM groups were significantly higher than those in NG group. This evidence concerns the gene HBA1 and Insulin resistance.