Chronic inflammation is an important pathophysiological factor leading to diabetes (6), which is manifested by higher levels of Nod-like receptor protein 3 (NLRP3), Caspase-1, Interleukin-1β (IL-1β), and various antiviral inflammatory cytokines (7), inducing a strong inflammatory response in the body. This evidence concerns the gene CASP1 and diabetes mellitus.