TNFSF13B and systemic lupus erythematosus: Interestingly, in addition to IL-6, IL-10, and IFN-γ (see above), we found overexpression of BAFF in the sera of B6/lpr-p2x7KO mice (Figure 6A), suggesting that the dysregulated production of these cytokines is responsible for the expression of SLE-associated serological biomarkers in B6/lpr-p2x7KO mice.