AIM2 inflammasomes scores were significantly increased in cancer samples than in normal samples, including in BLCA, CESC, COAD, DLBC, ESCA, GBM, HNSC, KIRC, KIRP, LAML, LGG, LIHC, OV, PAAD READ, SKCM, STAD, and TGCT (all P < 0.05). Here, AIM2 is linked to cancer.