AIM2 inflammasomes scores were expressed at lower levels in BRCA, LUAD, LUSC, PRAD, THYM, and UCS than in normal samples (all P < 0.05) (Figure 6B). Most tumors had higher AIM2 inflammasomes scores than normal samples, suggesting that AIM2 inflammasomes may play a vital role in tumor development. This evidence concerns the gene AIM2 and neoplasm.