GDNF (p ​= ​.017) was upregulated in PB of TSCI patients experiencing AIS grade conversion, while SIRT2 (p ​= ​.031) and IL1-alpha (p ​= ​.039) were downregulated in CSF of TSCI patients not experiencing AIS grade conversion. The gene discussed is GDNF; the disease is androgen insensitivity syndrome.