TARDBP and nervous system disorder: The TARDBP mutations identified in our cohort were instead absent in 1,710 Italian healthy controls, including 771 individuals with no reported history of neurological disorders that we previously screened (Corrado et al., 2009) and 939 subjects enrolled in other case-control studies (del Bo et al., 2009; Origone et al., 2010; Conforti et al., 2011; Gagliardi et al., 2018).