For 200 participants, significant results showed that higher serum PRR14 levels (37.82 vs. 30.26 ng/ml, P = 0.009; Figure 1A; Table 2) and VCAM-1 levels (1,098,200.00 vs. 440,188.30 pg/ml, P = 0.001; Figure 1B; Table 2) were observed in patients with PD than in HCs. This evidence concerns the gene PRR14 and Parkinson disease.