Univariate logistic regression analysis was conducted by taking collateral circulation as the dependent variable and age, gender, hypertension, diabetes, hyperlipidemia, history of coronary heart disease, history of stroke, smoking history, drinking history, WBC count, neutrophil count, lymphocyte count, NLR, UA, TC, TG, HDL, LDL, Hcy, Fib, HbA1c, CITED2, VEGF, and VEGF/CITED2 as independent variables. This evidence concerns the gene VEGFA and Stroke.