NTN1 and myocardial infarction: Consistent with a functional role of PMN-dependent netrin-1 in mediating DMOG-dependent cardioprotection, we found that the previously shown reduction of myocardial infarct sizes associated with DMOG treatment (Figures 5A–C) (5, 23) were completely abolished in Ntn1loxP/loxP LysM Cre+ mice (Figures 6C–E).