INS and atherosclerosis: Then, KEGG enrichment analysis was performed, and the results are shown in Figures 4A–C, which indicated that the target genes of tRF-60:76-Val-AAC-1-M5 might participate in regulation via the lipid and atherosclerosis pathway, the Ras signaling pathway, the NF-κB signaling pathway and insulin secretion (Table 5).