MAD2L1 was mainly expressed in the alveolar epithelium surrounding the fibrotic area and macrophages in lungs from patients with IPF and was weakly expressed in normal alveolar epithelium (Figure 1(b)), it also demonstrated that MAD2L1 was a dramatically upregulated in type II alveolar epithelial cells in IPF Cell Atlas Data (https://www.IPFcellatlas.com). This evidence concerns the gene MAD2L1 and idiopathic pulmonary fibrosis.