STAT3 and colorectal cancer: In colorectal-cancer-cell, EGCG activates caspase-3 for apoptosis, PARP, downregulation of STAT3 and phosphorylated STAT3 (p-STAT3), decreased Bcl-2 MCL-1, vimentin, along with the increase in E-cadherin (Luo et al., 2021).