ANXA2 and pancreatic neoplasm: ANXA2 expression has been shown to promote proliferation, invasion and metastasis in gliomas (Zhai et al., 2011), ovarian cancer (Lokman et al., 2013), hepatomas (Zhang et al., 2013), breast cancer (Sharma et al., 2006) and pancreatic cancer (Zheng et al., 2011).