ANXA5 and neoplasm: In addition, in vitro experiments have shown that ANXA5 depletion may hamper proliferation, migration, invasion and metastasis formation in various tumor cells from breast cancer (Bouvet et al., 2020), uterine cervical carcinoma (Li et al., 2018), hepatocarcinoma (Sun et al., 2018) and cholangiocarcinoma (Ding et al., 2017).