We thus found that miR-196a/b levels inversely correlated with ANXA1 expression in paired HNSCC tissue samples and that ANXA1 was a direct target of these miRNAs (Álvarez-Teijeiro et al., 2017a; Álvarez-Teijeiro et al., 2017b). The gene discussed is ANXA1; the disease is head and neck squamous cell carcinoma.