ANXA2 expression has been shown to promote proliferation, invasion and metastasis in gliomas (Zhai et al., 2011), ovarian cancer (Lokman et al., 2013), hepatomas (Zhang et al., 2013), breast cancer (Sharma et al., 2006) and pancreatic cancer (Zheng et al., 2011). The gene discussed is ANXA2; the disease is breast carcinoma.