CEACAM5 and neoplasm: To compare the predictive power between mRNF180 and serum tumor markers during the auxiliary diagnosis of GC, additional McNemer test and Kappa test were conducted in the GC group, and the results showed that the overall agreement was poor between both tests (Kappa values ranged from -0.010 to 0.196), and the positive rate of mRNF180 was significantly higher than that of CEA (P≦0.001), CA199 (P≦0.001), and CA724 (P≦0.001).