CLCN2 and posterior cortical atrophy: To evaluate the relationship between CLCN2 or CLCN6 expression levels and kinds of clinicopathological characteristics, statistically and more importantly, higher CLCN2 or CLCN6 expression in PCa tissues was positively correlated to high Gleason score (Figures 9E, F;Table 1, CLCN2, IRS: Gleason score > 7 = 7.03 ± 3.56 vs Gleason score ≤ 7 = 5.15 ± 3.46, P< 0.05; CLCN6, IRS: Gleason score > 7 = 7.13 ± 3.23 vs Gleason score ≤ 7 = 6.18 ± 2.76, P< 0.05).