Besides, the expression levels of CLCN2 and CLCN6 in PCa tissues was higher distinctly than that in benign prostate tissues (Figures 9C, D;Table 1, CLCN2, IRS: PCa = 6.05 ± 3.67 vs benign = 3.86 ± 2.14, P< 0.05; CLCN6, IRS: PCa = 6.77 ± 3.12 vs benign = 3.31 ± 1.84, P< 0.01). Here, IARS1 is linked to posterior cortical atrophy.