Alarin is also indicated to be involved in various disease conditions, such as obesity, metabolic syndrome (MetS), insulin resistance (IR), type 2 diabetes (T2DM), diabetic retinopathy, hypertension, cardiac fibrosis, polycystic ovarian syndrome (PCOS), and depression (9–12). This evidence concerns the gene GALP and obesity due to melanocortin 4 receptor deficiency.