For innate immune cells, we observed a significant decrease of tumor-infiltrating dendritic cells type 1 (TIDC1; CD45+CD11c+F4/80–CD11b+CD103– cells; Fig. 5A) and type 1 tumor-infiltrating macrophages (M1, CD45+CMH2+F4/80+CD11c–CD11b+ cells; Supplementary Fig. 2), and a significant increase of M2 (CD45+CMH2+F4/80+CD11c+CD11b+ cells; Supplementary Fig. 2) in male control mice compared with female control mice. Here, ITGAE is linked to neoplasm.