Baseline natriuretic peptide(NP)s have been shown to predict stroke, with N-Terminal Pro Brain Natriuretic Peptide (NT-proBNP) levels correlating to the degree of arteriosclerosis[33] and carotid plaque burden[34], both of which are associated with ischaemic stroke[35], [36]. The gene discussed is NPPB; the disease is Stroke.