GPT and metabolic dysfunction-associated steatotic liver disease: UA is the product of purine metabolism and can reflect the degree of insulin resistance and is involved in the occurrence and development of NAFLD through insulin resistance and activation of cytokines.22 Although the results of this study showed that the levels of AST, ALT and UA were increased in patients with T2DM and NAFLD, logistic regression analysis did not find those as a risk factor.