Specifically, m7Gcluster A was enriched in common oncogenic signaling pathways (e.g., mTOR, Notch and NSCLC signaling pathway), while lacked immune activation process (e.g., cytokine-cytokine receptor interaction, antigen processing and presentation), leading to the activation of abnormal biological characteristics including cell cycle, basal transcription factors, spliceosome, etc. (Figure 3A). The gene discussed is MTOR; the disease is non-small cell lung carcinoma.