Resveratrol can effectively improve atrial fibrillation by inhibiting NADPH oxidase and ion channels (Barangi et al., 2018), and like curcumin, it also acts as an anti-inflammatory agent by inhibiting neutrophil activation (Tsai et al., 2019), and attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis (Li et al., 2022). Here, FMO5 is linked to atrial fibrillation.