MAPK8 and rectum adenocarcinoma: As shown in Figure 10 and Table S8, REV1 expression is negatively correlated with IC50 of drugs of DNA replication, hormone-related, JNK and p38 signaling, kinases, protein stability and degradation, RTK signaling, and WNT signaling pathways in colon adenocarcinoma and rectum adenocarcinoma and drugs of kinases, RTK signaling, and WNT signaling pathways in lung adenocarcinoma.