All other WBC cell classes in blood (Figures 2C,D) and spleen (Figures 2E,F) in MecomJbo/+ and Mecom+/+, and in Fbxo11Jf/+ and Fbxo11+/+ comparisons were not significantly different suggesting that OM is not associated with substantial peripheral blood leukogram or spleen changes. The gene discussed is FBXO11; the disease is ocular melanoma.