The results showed that activated FANCD2 was positively enriched in the cell cycle, p53 signaling pathway, mTOR signaling pathway, DNA replication, TGF-beta signaling pathway, Wnt signaling pathway, and RNA degradation (p < 0.05; Figure 11), revealing the tumor-associated and even tumor-promoting roles of FANCD2 and shedding light on its potential mechanisms in HCC. Here, TP53 is linked to neoplasm.