Compared with normal specimens, CD8 T cells, follicular helper T cells, gamma delta T cells, resting NK cells, activated NK cells, M1 macrophages, M2 macrophages, resting dendritic cells, activated dendritic cells, endothelial cells and fibroblasts exhibited higher enrichment levels in IgA nephropathy (Figure 5B). This evidence concerns the gene CD8A and IgA glomerulonephritis.