TP53 and cancer: As shown in Figures 3A–E, SPOCK2 mRNA expression level was significantly correlated with patient’s race (Caucasian vs. African-american, p < 0.01) and tumor grade (Grade 2 vs. Grade 3, p < 0.05), and has no relation with patient’s age, individual cancer stage, and TP53 mutation status (p > 0.05).