A list of 14 intersectional genes was extracted, of which 11 were upregulated and 3 were downregulated in GSE13159 and TCGA LAML (Figure 2C), including IL1R2, MMP8, FGF13, SLC25A21, etc. In pan-cancer analysis, we determined the expression profiles of these genes in normal and malignant samples. The gene discussed is MMP8; the disease is cancer.